EP 144: Real Confidence- Confidence, Conflict and Your Exhausted Brain

Ever finish a perfectly ordinary workday feeling like you've run a marathon? You answered emails, sat through meetings, dealt with a few difficult personalities and somehow arrived at 5 p.m. with absolutely nothing left for the people or things you actually enjoy.

And the maddening part? You’ll probably do it all again tomorrow.

My dear friend Bruna De Palo, a fellow neuro nerd, neuroscience executive coach and one of my favorite humans, has a fascinating explanation for why we make life so much harder on ourselves than it needs to be. And it starts with something our brains are very, very good at: conserving energy.

Bruna's new book, The Brain Instruction Manual for Leaders, explores what happens when the way we work, communicate and lead is fundamentally at odds with how our brains are designed to function. We're burning through precious mental energy on misunderstandings, unnecessary conflict and trying to get people to do things in ways that actually make their brains less effective. Brilliant strategy, right?

Now, you know I'm all about confidence and brain science, so this conversation was right up my alley. Because when someone feels threatened, dismissed or backed into a corner, their brain responds accordingly. And good luck getting their best thinking, cooperation or confidence when that happens. The really interesting part is how often we create those conditions without even realizing it.

What I love about Bruna's approach is that she doesn't ask us to become nicer people just because it's the right thing to do. She makes a compelling case that understanding how brains work can make us more effective and leave us with more energy for our actual lives. And you don't need to manage a team to benefit. If you deal with other human beings (and I'm guessing you do), this conversation is for you.

Highlights from our conversation:

  • Why an ordinary workday can leave your brain feeling completely spent
  • The surprising price we pay for trying to get the best out of other people
  • Why the leadership approach that once got results may now be working against you
  • How understanding someone else's brain can change a disagreement without changing either person's opinion
  • Where the line falls between understanding human behavior and manipulating it

Bruna De Palo is a neuroscience executive coach, keynote speaker and creator of the B.R.A.I.N. Leadership Model™. Drawing on nearly two decades of corporate experience and neuroscience studies at MIT Sloan, she helps leaders understand how the brain shapes behavior, performance and workplace culture. A faculty member at the NeuroLeadership Institute, Bruna works with Fortune 500 organizations worldwide and was recognized among Thinkers50’s Global Top 50 Executive Coaches in 2026. She is the author of The Brain Instruction Manual for Leaders. Learn more about Bruna at brunadepalo.com.